As leading Harvard Medical Doctors have been telling us for years, Testosterone Replacement Therapy does not cause cancer.

Men who undergo testosterone replacement therapy due to a drop in testosterone levels might not be at an increased risk of getting prostate cancer as previously thought, a new study from the U.K. suggests.

Researchers looked at nearly 1,400 men receiving testosterone replacement therapy for up to 20 years, and found that 14 cases of prostate cancer developed over the study period.

That number equates to one prostate cancer diagnosis yearly per 212 men; in the general population of U.K. men between ages 65 and 69, rates have been reported to be slightly less than one in 200 per year.

“This myth about testosterone replacement therapy being linked to prostate cancer has been rooted deep in medical consciousness for over 60 years,” said study co-author, Dr. Malcolm Carruthers, medical director at the Center for Men’s Health in London. “But this paper says no, testosterone treatment is actually good for the prostate, not bad.”

The study was published online June 6 in the Journal of Sexual Medicine.

Aging men sometimes experience “andropause”

Testosterone Levels vary greatly among men, but generally tend to drop with aging, sometimes causing them to experience a so-called “andropause.”

But unlike female menopause, which happens to all women as they age, not all men lose testosterone as they age, and the condition can also be overlooked, since the drop in hormone is gradual.

According to the Mayo Clinic , however, by age 70, a man’s testosterone level can drop by as much as 50 percent.

With the drop, men can experience a number of symptoms, including reduced sexual desire, fatigue, depression, bone loss and increased body fat.

Testosterone replacement therapy can reverse these symptoms.

“Evidence is rapidly accumulating that, not only is testosterone treatment important in maintaining a man’s vitality and virility over the age of 50,” Carruthers said, “but also in the treatment of a wider range of serious physical and mental illnesses.”

But that may not always be the case when it comes to men who have already been treated for prostate cancer, according to Dr. Paul Nguyen, a radiation oncologist at Dana-Farber Cancer Institute in Boston.

“About 230,000 men a year are diagnosed with prostate cancer, and for those who have low testosterone after treatment, whether it’s safe to treat them with testosterone remains a big issue,” he said.

Testosterone treatment could improve quality of life

Researchers looked at 1,365 men participating in the ongoing U.K. Androgen Study. The men were treated with testosterone for at least three months for up to 20 years.

The researchers calculated that for every 10 men taking testosterone for 21 years, one would develop prostate cancer. In most cases, the cancer was detected with a test of prostate-specific antigen (PSA), a protein that suggests the presence of prostate cancer when found at high levels.

Based on study results, the researchers said that testosterone treatment is safe when carefully monitored.

As always, a larger study with longer follow-up would make doctors feel even more confident, Nguyen said. But he added the study was reassuring because of its size.

“For people with low testosterone who are thinking about getting treatment, this study helps to reduce the concern,” Nguyen said.

“So, it gives them the freedom to pursue this treatment, which can improve their quality of life.”

Pass it on: Testosterone treatment may not increase risk of prostate cancer.

Boston Testosterone is a Testosterone Replacement, Wellness and Preventative Medicine Medical Center that treats and prevents the signs and symptoms associated with Andropause and hormone imbalances. With affiliates nationally, Boston Testosterone offers hormone replacement therapy, weight loss protocols, erectile dysfunction (ED), Sermorelin-GHRP2 therapy and neutraceutical injectable therapies for men and women. Their medical facilities offer physician examinations and treatment programs that incorporate the latest in medical science.

“The Greatest Health of Your Life” ℠

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www.BostonTestosterone.com

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By Linda Thrasybule, My Health News Daily

Testosterone Replacement Therapy has been shown to help men with diabetes, says new study.

Diminished energy, reduced lean muscle mass, decreased libido, erectile dysfunction…these symptoms are common in men with low levels of the hormone testosterone. Men with type 2 diabetes are particularly prone to this hormonal deficiency—it affects about one-third of them—and it can make their blood sugar problems even worse. Good news: Testosterone replacement therapy has multiple benefits for such men, a recent study shows.Participants included 81 men with diabetes. Some had normal levels of free testosterone (the amount of the hormone in the bloodstream)…some had low levels of less than five nanograms per deciliter (ng/dL). At the start of the study, all the men were given a battery of tests and, as expected, men with low testosterone had a bunch of problems. They had more body fat, less lean muscle and more inflammation, and they were more insulin-resistant—meaning their bodies were less able to recognize and respond to insulin.

Next, the men with low testosterone were divided into two groups. One group received injections of testosterone every two weeks for 24 weeks…the other group received placebo injections.

What the testosterone did: In the placebo group, nothing improved. However, among the men who received testosterone injections, insulin resistance improved by nearly 30%—and that was enough of an improvement to essentially get rid of their insulin resistance. What’s more, these men lost an average of 4.5 pounds of fat and gained 4.5 pounds of lean muscle…their inflammation decreased…and they reported significant improvement in libido and increased satisfaction with their erections.

Men with diabetes: Doctors generally do not screen diabetes patients for testosterone deficiency , so ask to be tested—it is a simple and inexpensive blood test. If your free testosterone level is below five ng/dL, talk to your doctor about bringing it back up to normal with testosterone replacement therapy. There are four forms of testosterone therapy—injections, topical gel, topical custom-compounded cream and surgically inserted pellets. The treatment could make it easier for you to manage your diabetes by lessening your insulin resistance…and it could boost your energy, strength and sex life, as well.

Reassuring: For decades, it was believed that increasing testosterone made prostate tumors grow, but there is now strong evidence that raising testosterone levels in men who have testosterone deficiency does not increase prostate cancer risk.

Source: Sandeep Dhindsa, MD, endocrinologist and associate professor, State University of New York at Buffalo. His research was presented at the 2013 meeting of the American Association of Clinical Endocrinologists.

If you would like to find out your testosterone levels or if you have previously been diagnosed as suffering from Low Testosterone, Hypogonadism or Andropause, contact us.

Send us an email for information on our practice, our TRT protocols and our adjunct therapies: cblaisdell@corenewengland.com.

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A new study finds that a drop in testosterone levels over time is more likely to result from a man’s behavioral and health changes than by aging.

“Declining testosterone levels are not an inevitable part of the aging process, as many people think,” said study co-author Gary Wittert, MD, professor of medicine at the University of Adelaide in Adelaide, Australia. “Testosterone changes are largely explained by smoking behavior and changes in health status, particularly obesity and depression.”

Many older men have low levels of the sex hormone testosterone , but the cause is not known. Few population-based studies have tracked changes in testosterone levels among the same men over time, as their study did, Wittert said.

In this study, supported by the National Health and Medical Research Council of Australia, the authors analyzed testosterone measurements in more than 1,500 men who had measurements taken at two clinic visits five years apart. All blood testosterone samples underwent testing at the same time for each time point, according to Wittert.

After the researchers excluded from the analysis any men who had abnormal lab values or who were taking medications or had medical conditions known to affect hormones, they included 1,382 men in the data analysis. Men ranged in age from 35 to 80 years, with an average age of 54.

On average, testosterone levels did not decline significantly over five years; rather, they decreased less than 1 percent each year, the authors reported. However, when the investigators analyzed the data by subgroups, they found that certain factors were linked to lower testosterone levels at five years than at the beginning of the study.

“Men who had declines in testosterone were more likely to be those who became obese, had stopped smoking or were depressed at either clinic visit,” Wittert said. “While stopping smoking may be a cause of a slight decrease in testosterone, the benefit of quitting smoking is huge.”

Past research has linked depression and low testosterone . This hormone is important for many bodily functions, including maintaining a healthy body composition, fertility and sex drive. “It is critical that doctors understand that declining testosterone levels are not a natural part of aging and that they are most likely due to health-related behaviors or health status itself,” he said.

Unmarried men in the study had greater testosterone reductions than did married men. Wittert attributed this finding to past research showing that married men tend to be healthier and happier than unmarried men. “Also, regular sexual activity tends to increase testosterone ,” he explained.

Source: The Endocrine Society

Boston Testosterone is a Testosterone Replacement , Wellness and Preventative Medicine Medical Center that treats and prevents the signs and symptoms associated with Andropause and hormone imbalances. With affiliates nationally, Boston Testosterone offers hormone replacement therapy, weight loss protocols, erectile dysfunction (ED), Sermorelin-GHRP2 therapy and neutraceutical injectable therapies for men and women. Their medical facilities offer physician examinations and treatment programs that incorporate the latest in medical science.

“The Greatest Health of Your Life” ℠

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Low testosterone levels have been linked to a marker of whole body inflammation, C Reactive Protein. When germs, high levels of fat in blood or high blood pressure are present they cause cellular injury, resulting in inflammation of the body. Harboring inflammation over an extended period of time can lead to tissue destruction and a variety of health problems such as allergies, cancer, arthritis and autoimmune diseases.

A recent study has found a link that was very strong in overweight men as well as those with the risk factors of heart disease, such as low testosterone . High blood pressure, obesity, diabetes, smoking and high blood fats were positively linked to increased C Reactive Protein, therefore inflammation.

Very importantly, higher levels of total testosterone (TT, β = −0·114, 95%CI, −0·162 to −0·065), free testosterone (β = −0·059, 95%CI, −0·106 to −0·012) and SHBG (β = −0·116, 95%CI, −0·169 to −0·063) were statistically significantly related to lower levels of C Reactive Protein (Clinical Endocrinology, 78: 60-66, 2013).

The clinical studies surrounding the associated dangers of low testosterone (LOW T) in men are staggering.

If you are a man of 30 years of age and feel you may be suffering from Low Testosterone, Hypogonadism or Andropause, contact Boston Testosterone Partners today for a consult on how you can get tested.

Boston Testosterone is a Testosterone Replacement, Wellness and Preventative Medicine Medical Center that treats and prevents the signs and symptoms associated with Andropause and hormone imbalances. With affiliates nationally, Boston Testosterone offers hormone replacement therapy, weight loss protocols, erectile dysfunction (ED), Sermorelin-GHRP2 therapy and neutraceutical injectable therapies for men and women. Their medical facilities offer physician examinations and treatment programs that incorporate the latest in medical science.

“The Greatest Health of Your Life” ℠

Boston Testosterone Partners/Core New England

www.BostonTestosterone.com

www.facebook.com/BostonTestosterone

CBlaisdell@CoreNewengland.com

781-269-5953

Study finds patients with deficiency more likely to be poorer and without insurance

Boston Testosterone Partners, Men’s Health Clinic.

Boston, Massachusetts – (HealthDay News) — Many men with low testosterone levels don’t receive treatment, even though they have access to care, according to a U.S. study. The study, which received funding from drug maker GlaxoSmithKline, was published in the May 26 issue of the journal Archives of Internal Medicine.

The research involved 97 Boston-area men with the low testosterone, also known as androgen deficiency. Only 11 were prescribed treatment. Treatments included: testosterone gel (one patient); testosterone patch (three patients); testosterone cream (one patient); an injectable form of testosterone called testosterone cypionate (one patient); and unspecified formulations of testosterone (five patients).

“All of the unspecified forms of testosterone used were self-reported as administered in intervals defined in weeks, which suggests that these were injectable formulations,” wrote Susan A. Hall, of New England Research Institutes in Watertown, Mass., and colleagues.

Men with untreated androgen deficiency were most likely to have low socioeconomic status, no health insurance and to rely on an emergency department or hospital outpatient clinic for primary care, the study authors said.

They also found that all men with androgen deficiency (treated and untreated) were more likely than men without the condition to report receiving regular care and visiting their doctor more often — 15.1 visits per year for those with untreated androgen deficiency, 12 visits for those with treated androgen deficiency, and 6.7 visits for those without the condition.

“Under our assumptions, a large majority (87.8 percent) of 97 men … with androgen deficiency were not receiving treatment despite adequate access to care. The reasons for this are unknown but could be due to unrecognized androgen deficiency or unwillingness to prescribe testosterone therapy,” the study authors wrote.

Symptoms of androgen deficiency include low libido, erectile dysfunction, osteoporosis, sleep disturbance, depressed mood and tiredness.

US News and World Reports

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Originally Published by Life Extension Magazine

By Kirk Stokel

In 2007, Life Extension® led the battle against Congress’s ill-conceived campaign to re-classify DHEA (dehydroepiandrosterone) as an “anabolic steroid drug” — an act that would have made this life-sustaining compound unavailable to the American public without a prescription.

Today, less than three years later , scientists have uncovered even more research substantiating DHEA’s remarkable health-promoting benefits.

Sometimes called the “youth hormone,” DHEA is the most abundant hormone precursor in the human body and a source of the sex hormones.

Its steady and precipitous decline is an inevitable consequence of aging, (1) and contributes to the onset of degenerative disease.

The latest scientific discoveries indicate that as little as 50 mg of DHEA per day may:

1. Inhibit multiple factors implicated in metabolic syndrome by favorably altering gene expression;
2. Boost bone strength and ward off osteoarthritis;
3. Enhance memory.(2-5)

Daily intake of 90 mg per day and higher has been shown to improve cognitive function and alleviate depression both in the elderly and among individuals suffering from debilitating mental illness. (6,7)

In this article, you will discover the most up-to-date evidence of DHEA’s profoundly beneficial impact across multiple systems of the body.

Potent Cognitive Support

DHEA deficiency is implicated in numerous age-related conditions, including declines in brain and nervous system function. The latest research suggests that DHEA supplementation may exert powerful neuroprotective effects.

In fact, 2009 witnessed extraordinary advances in our understanding of the cognitive and memory-enhancing benefits of DHEA.

Two large studies showed that levels of DHEA-S in elderly patients correlated significantly and positively with cognitive function. (Chemically similar to DHEA, DHEA-S is the sulfated form of DHEA.)(8,9) Prior research had shown that higher DHEA-S levels were directly associated with improved concentration, working memory, and executive (decision-making) function.(10)

Israeli scientists found that the cognitive dysfunction that occurs in schizophrenia is also partly associated with levels of DHEA-S and other neurosteroids.(11) Supplementation with 200 mg per day of DHEA in schizophrenic patients improved attention and motor skills compared with placebo.(6) Although the direct symptoms of schizophrenia were unaffected, DHEA’s ability to provide relief from the cognitive deficits associated with this severe psychiatric condition may significantly improve quality of life in these individuals.

The last few years have also yielded new pre-clinical data on DHEA’s neuroprotective, memory-enhancing effects. In one noteworthy study, DHEA significantly improved memory retention and consolidation in mice—especially when the experimental equivalent of an emotional stimulus was involved.(12) This may be related to DHEA’s ability to stimulate the proliferation of key brain cell receptors specifically associated with memory processing.(13)

When given to aging rats, DHEA was shown to enhance brain cell utilization of ATP—the body’s fundamental energy-storage molecule—thereby protecting the cell membranes from age-related damage.(14) Impaired energy utilization and reduced production of ATP contribute to the “neuronal energy crises” that underlie Alzheimer’s and other neurodegenerative diseases.(15)

A landmark 2007 study showed that DHEA supplementation of 150 mg twice daily improved memory recall and mood in healthy young men, specifically increasing activity in the hippocampus, the region of the brain most closely associated with mnemonic function (memory).(5)

Enhance Your Mood—Naturally

Depression often accompanies aging, frequently emerging in older individuals.(16,17) Fortunately, we now recognize depression as an essentially physiological condition—one that can be treated. Low DHEA levels are known to render aging humans more vulnerable to depression in the presence of triggers such as rejection or isolation.(18) Negative emotional stimuli have been shown to lower DHEA levels even further.(19)

Supplementation with DHEA can powerfully mitigate depression and its effects. A National Institute of Mental Health study of depressive men and women aged 45-65 years showed significant improvement over 6 weeks among those who took 90 mg of DHEA per day for 3 weeks and then 450 mg per day for 3 weeks, compared with placebo.(7)The study also showed significant improvements in sexual functioning scores in supplemented patients, but not among control patients. In a rare admission from the generally conservative National Institute of Mental Health, their conclusion was, “We find DHEA to be an effective treatment for midlife-onset major and minor depression.”

In a set of studies, DHEA was found to improve both mood and energy while alleviating depression.(20-22) Israeli researchers also demonstrated minimal effects on other hormonal profiles, alleviating concerns about adverse events with DHEA.(23)

A remarkable 2006 study demonstrated reduction in depressive symptoms in an especially challenging population—patients with HIV/AIDS.(24)

Several 2009 studies revealed associations of low DHEA levels with a number of neuropsychiatric conditions and were able to show that DHEA influences gene expression in the brain.(25) For example, DHEA modulates expression of genes directly involved in appetite regulation, energy utilization, and alertness.(26) Another study demonstrated that DHEA acted in synergy with the antidepressant fluoxetine (Prozac®), leading researchers to suggest DHEA as “a useful adjunct therapy for depression.”(27)

Support for Aging Bones and Joints

A 2000 study demonstrated improved bone turnover—more marked in women than in men—during a year-long study of daily 50 mg supplementation with DHEA.(28) (Bone turnover is the natural process by which the body replaces old bone from the skeleton and replaces it with new bone.) By 2003, laboratory evidence emerged suggesting that DHEA could potentially enhance joint function and ward off osteoarthritis (OA).(2)

DHEA treatment of cartilage tissue taken from patients with OA increased production of healthy, flexible type II collagen protein, while reducing production of the less flexible type I collagen associated with scar formation.2 DHEA also modified the imbalance between cartilage-destroying enzymes and those that protect cartilage from damage. These impressive effects were the direct result of DHEA’s capacity to favorably modulate gene expression.

DHEA’s effects on bone structure are no less significant. A double-blind, randomized, controlled trial of 50 mg per day of DHEA administered orally versus placebo for 12 months showed improved hip bone mineral density (BMD) in older men and women with low DHEA-S levels, with additional improvements in spine BMD in women.(3,29) A larger study in 2008 showed that DHEA not only improved lumbar spine BMD in women (not men) taking 50 mg per day for a year, but it also reduced blood-borne markers of bone resorption,(30) an important measure of overall bone health and bone aging. Not surprisingly, the addition of vitamin D and calcium supplements to a DHEA regimen may afford further benefit.(31)

Optimal Immune Strength and Anti-Viral Protection

The precipitous age-related decline in DHEA/DHEA-S levels results in the immune deficiency we call immunosenescence.(32) Supplementation with DHEA may beneficially modulate immunity(33,34) to help combat debilitating age-related conditions through multiple, complementary pathways.

DHEA has boosted immune function in blood cells taken from patients after major abdominal surgery.(35) This action may help to prevent serious infections and promote healing. In the setting of dangerous infections and trauma in laboratory animals, DHEA and its metabolites markedly upregulate host immune responses, modulate inflammation, and improve survival.(36-38) In animal models, DHEA’s ability to raise sex hormone concentrations to youthful levels also promoted wound healing.(39)

DHEA also possesses significant antiviral properties. It has blocked replication of several different, potentially deadly virus families in the laboratory—more effectively and more selectively than the drug ribavirin! (40,41)

A 2008 study showed that DHEA also increases natural resistance to certain lethal parasites, including Trypanosma cruzi (the cause of Chagas disease),(42) a microorganism that causes death from heart disease and brain damage, particularly in immunocompromised patients. Subsequent research conducted in 2009 found that DHEA supplementation reduced parasite levels, raised levels of defensive macrophage white blood cells, and increased levels of immune signalling interferons.(43,44)

Among individuals stricken with autoimmune disorders such as rheumatoid arthritis or lupus, treatment with conventional corticosteroids not only over-suppresses the immune system, it can also promote bone resorption and catastrophic fractures. DHEA has been shown to reduce expression of cytokines and other factors that lead to bone resorption in steroid-treated tissue, while still suppressing inflammation effectively.(45)

There’s good news for asthma and allergy patients who respond poorly to regular steroid usage as well. DHEA is now known to suppress allergy-induced inflammatory cytokines in reactive airway cells while increasing the ratio of beneficial interferon to inflammatory cytokines—highly significant advances in the management of this troubling condition.(46)

Combat Metabolic Disorders

We’ve known for over a decade that DHEA protects against obesity and its consequences in aging and diabetic animals .(47,48) In 2009, scientists confirmed that low DHEA levels in men were linked to diabetes and coronary heart disease.(49) DHEA powerfully modulates gene expression to shift the metabolic balance in favor of energy utilization and away from storage as fat.(50)

DHEA also activates gene expression of cellular machinery that affects a cell’s consumption of fats and sugars to remove them from circulation.(51,52) These molecules help correct harmful lipid abnormalities and unhealthy body fat distribution—a possible mechanism by which DHEA decreases total body fat.(53,54)

In 2007, researchers demonstrated in aged rats fed a high-fat diet that DHEA increased body protein, while decreasing total caloric intake, body weight, body fat, and total size and number of fat cells.(5)5 In a related experiment, researchers discovered that DHEA could change the composition of adipose tissue, boosting levels of beneficial omega-3 fatty acids while reducing harmful omega-6 fatty acids. (56)

A human study showed how powerfully these DHEA effects can modify body composition.(4) When 52 elderly men and women took 50 mg per day of DHEA or placebo for 6 months, it reduced stubborn abdominal and subcutaneous body fat. Insulin levels dropped significantly in supplemented patients as well, indicating enhanced insulin sensitivity. The researchers concluded appropriately that “DHEA replacement could play a role in prevention and treatment of the metabolic syndrome associated with abdominal obesity.” “DHEA replacement could play a role in prevention and treatment of the metabolic syndrome associated with abdominal obesity.”

DHEA is highly protective against diabetes and its complications. In diabetic rats, DHEA prevented increases in oxidant stress and oxidative damage related to the disease. It also significantly improved blood vessel relaxation, improving blood flow.(57) DHEA induces genes in muscle tissue that increase uptake and utilization of blood glucose as energy, significantly lowering blood sugar in diabetic animals.(58) In humans with type 2 diabetes, DHEA counteracts oxidative imbalance and the formation of deadly advanced glycation end products (AGEs), and downregulates the inflammatory TNF-alpha system—effects that may prevent the onset and slow the progression of deadly diabetes. (59)

Cardiovascular Disease Defense

The past several years have witnessed extraordinary advances in our understanding of DHEA’s cardioprotective power—and its relationship to cardiovascular disease.

A 2009 study of 153 diabetic men with stable coronary heart disease (CHD) found that 77% were DHEA-S deficient, significantly more than in healthy peers.(60) Over the next 19 months of follow-up, 43 of those men died of CHD; the data showed that low DHEA-S and low testostosterone levels were two of the four most significant predictors of death.

Another 2009 study of 247 men with a mean age of 76 years revealed that those with low DHEA-S had a 96% increased risk of diabetes and a 48% increased risk of coronary heart disease. (49)

A 2009 study from the University of Pennsylvania discovered a surprisingly close relationship between mortality and the trajectory of DHEA-S decline in older adults.(61) Specifically, a rapid or erratic decline in DHEA-S predicted earlier death, and both together increased the death rate by nearly threefold! Regular blood testing for healthy DHEA-S levels are the only way to detect these lethal changes in DHEA levels early. It is of paramount importance that you have your DHEA-S levels checked at least once a year.

A Mayo Clinic study found that DHEA supplementation (50 mg per day) in women with low DHEA levels and low adrenal function improved plasma DHEA content, significantly lowered total cholesterol, and tended to reduce triglyceride and low-density lipoprotein (LDL) levels. (62) But supplemented patients also had reductions in their beneficial high-density lipoprotein (HDL) levels. This study suggests that long-term studies are needed to determine the impact of DHEA supplementation on cardiovascular risk in women with low adrenal function.

Additional support for DHEA’s benefits in patients suffering from vascular disease came in two remarkable 2009 studies.(63,64) The first examined vascular remodeling, a dangerous process that occurs when vessels are injured by atherosclerosis.(63) Vascular remodeling can impede blood flow and ultimately worsen cardiovascular disease.(65)

DHEA significantly inhibited vascular remodeling in a rabbit model of carotid artery injury and limited deadly buildup of smooth muscle in vessel walls.(63) Another study of rabbits fed a high-fat diet showed that DHEA supplements restored oxidative balance, lowered lipid levels and inflammatory damage, and prevented heart muscle tissue death and dysfunction, delaying the onset of cardiac damage.(64)

Enhanced Well-Being and Libido Even in Challenged Populations

Studies as early as 2000 demonstrated how DHEA improved well-being and could help to manage menopause without deleterious effects.(28,66) In 2006 it was revealed that 50 mg per day of DHEA could improve psychological well-being even in challenging populations such as those with decreased pituitary function.(67)

DHEA exerted a remarkably positive effect on health-related quality of life in women taking long-term steroids for lupus (chronic steroid therapy can produce powerful depression and reduction in quality of life measures).(68) Of particular importance, the DHEA-supplemented groups also reported improvement in sexuality.

Additional research supports an excitatory effect for DHEA on sexuality—especially in women. In one study, sixteen sexually functional postmenopausal women were randomly given either placebo or a single DHEA supplement of 300 mg, 60 minutes before presentation of an erotic video.(69) Women in the supplement group showed significantly greater mental and physical sexual arousal during the video than did the control women. The supplemented women also reported a greater increase in positive affect (generally feeling good) compared to placebo recipients.

A 2009 animal study may shed light on some of the physical causes behind these benefits: DHEA applied to the smooth muscle of rabbit clitoris resulted in significant relaxation,(70) allowing the increased blood flow and engorgement that results in enhanced sensitivity during sexual arousal.

Favorable Gene Expression for Youthful, Glowing Skin

A growing body of scientific evidence suggests that DHEA has especially favorable effects on skin health and appearance. In a 2000 laboratory study, DHEA was shown to increase production of collagen—the protein that gives youthful skin its suppleness—while decreasing production of the collagenase enzymes that destroy it.(71)

It wasn’t until 2008, however, that Canadian scientists discovered more than 50 DHEA-responsive genes in the skin of women using a topical DHEA crème. (72) DHEA “switched on” multiple collagen-producing genes and reduced expression of genes associated with production and cornification (hardening) of the tough keratinocytes that form calluses and rough skin. The researchers concluded, “DHEA could exert an anti-aging effect in the skin through stimulation of collagen biosynthesis, improved structural organization of the dermis while modulating keratinocyte metabolism.”

Other unexpected benefits of topical DHEA on aging skin are emerging. DHEA treatment increases production of sebum, or skin oil.(73) Sebum not only contributes to smooth, supple skin; it also contains myriad antimicrobial components that prevent infection and irritation. Topical DHEA also improves skin “brightness” and counteracts the “papery” appearance of aging skin, combating the epidermal thinning that is a visible hallmark of aging.(73) The study authors note that these are “beneficial effects on skin characteristics that are rarely provided by topical treatments.”

Summary

In the past few years alone, significant scientific substantiation of DHEA’s anti-aging effects has emerged. Its neuroprotective effects are now recognized as being vital in protecting memory and reducing depressive symptoms in older adults. DHEA enhances bone health by improving mineralization to reduce fracture risk. DHEA modulates immunity in a coordinated fashion, boosting resistance to infection while quelling dangerous inflammation. DHEA supports cardiovascular health and activates genes that prevent cardiovascular risk factors, including diabetes and obesity. DHEA is intimately involved in improving quality of life and bolstering sexual arousal, while dramatically improving the appearance of healthy, youthful skin. As little as 50 mg of DHEA per day may favorably alter gene expression to inhibit multiple factors implicated in metabolic syndrome; boost bone strength; enhance cognitive function and memory; and ward off osteoarthritis. DHEA topical crèmes allow ready application of DHEA to the site of action.

Note: Individuals who have been diagnosed with a hormone-dependent cancer should not supplement with DHEA until their cancer is cured.

The Health & Rejuvenation Center offers various therapies for our patients and comprehensive health screenings, including DHEA Therapy and Testosterone Therapy. If you would like to learn more, just follow this link and fill out our short Contact Form for a Free Consultation or Call Us at 800-466-2209 to speak with one of our Clinical Assistants.

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2. Jo H, Park JS, Kim EM, et al. The in vitro effects of dehydroepiandrosterone on human osteoarthritic chondrocytes. Osteoarthritis Cartilage. 2003 Aug;11(8):585-94.

3. Jankowski CM, Gozansky WS, Schwartz RS, et al. Effects of dehydroepiandrosterone replacement therapy on bone mineral density in older adults: a randomized, controlled trial. J Clin Endocrinol Metab. 2006 Aug;91(8):2986-93.

4. Villareal DT, Holloszy JO. Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial. JAMA. 2004 Nov 10;292(18):2243-8.

5. Alhaj HA, Massey AE, McAllister-Williams RH. Effects of DHEA administration on episodic memory, cortisol and mood in healthy young men: a double-blind, placebo-controlled study. Psychopharmacology (Berl). 2006 Nov;188(4):541-51.

6. Ritsner MS, Gibel A, Ratner Y, Tsinovoy G, Strous RD. Improvement of sustained attention and visual and movement skills, but not clinical symptoms, after dehydroepiandrosterone augmentation in schizophrenia: a randomized, double-blind, placebo-controlled, crossover trial. J Clin Psychopharmacol. 2006 Oct;26(5):495-9.

7. Schmidt PJ, Daly RC, Bloch M, et al. Dehydroepiandrosterone monotherapy in midlife-onset major and minor depression. Arch Gen Psychiatry. 2005 Feb;62(2):154-62.

8. Fukai S, Akishita M, Yamada S, et al. Association of plasma sex hormone levels with functional decline in elderly men and women. Geriatr Gerontol Int. 2009 Sep;9(3):282-9.

9. Valenti G, Ferrucci L, Lauretani F, et al. Dehydroepiandosterone and cognitive function in the elderly: The InCHIANTI Study. J Endocrinol Invest. 2009 Oct;32(9):766-72.

10. Davis SR, Shah SM, McKenzie DP, Kulkarni J, Davison SL, Bell RJ. Dehydroepiandrosterone sulfate levels are associated with more favorable cognitive function in women. J Clin Endocrinol Metab. 2008 Mar;93(3):801-8.

11. Ritsner MS, Strous RD. Neurocognitive deficits in schizophrenia are associated with alterations in blood levels of neurosteroids: A multiple regression analysis of findings from a double-blind, randomized, placebo-controlled, crossover trial with DHEA. J Psychiatr Res. 2010 Jan;44(2):75-80.

12. Bazin MA, El Kihel L, Boulouard M, Bouët V, Rault S. The effects of DHEA, 3beta-hydroxy-5alpha-androstane-6,17-dione, and 7-amino-DHEA analogues on short term and long term memory in the mouse. Steroids. 2009 Nov;74(12):931-7.

13. Chen C, Lang S, Zuo P, Yang N, Wang X. Treatment with dehydroepiandrosterone increases peripheral benzodiazepine receptors of mitochondria from cerebral cortex in D-galactose-induced aged rats. Basic Clin Pharmacol Toxicol. 2008 Dec;103(6):493-501.

14. Taha A, Mishra M, Baquer NZ, Sharma D. Na+ K(+)-ATPase activity in response to exogenous dehydroepiandrosterone administration in aging rat brain. Indian J Exp Biol. 2008 Dec;46(12):852-4.

15. de la Torre JC. Pathophysiology of neuronal energy crisis in Alzheimer’s disease. Neurodegener Dis. 2008;5(3-4):126-32.

16. Camus V. Evaluation of the depressive symptomatology in the elderly. Psychol Neuropsychiatr Vieil. 2004 Sep;2 Suppl 1:S13-17.

17. Djernes JK. Prevalence and predictors of depression in populations of elderly: a review. Acta Psychiatr Scand. 2006 May;113(5):372-87.

18. Akinola M, Mendes WB. The dark side of creativity: biological vulnerability and negative emotions lead to greater artistic creativity. Pers Soc Psychol Bull. 2008 Dec;34(12):1677-86.

19. Wang HT, Chen SM, Lee SD, et al. The role of DHEA-S in the mood adjustment against negative competition outcome in golfers. J Sports Sci. 2009 Feb 1;27(3):291-7.

20. Strous RD, Maayan R, Lapidus R, et al. Dehydroepiandrosterone augmentation in the management of negative, depressive, and anxiety symptoms in schizophrenia. Arch Gen Psychiatry. 2003 Feb;60(2):133-41.

21. Herbert J. Neurosteroids, brain damage, and mental illness. Exp Gerontol. 1998 Nov-Dec;33(7-8):713-27.

22. Bloch M, Schmidt PJ, Danaceau MA, Adams LF, Rubinow DR. Dehydroepiandrosterone treatment of midlife dysthymia. Biol Psychiatry. 1999 Jun 15;45(12):1533-41.

23. Strous RD, Maayan R, Kotler M, Weizman A. Hormonal profile effects following dehydroepiandrosterone (DHEA) administration to schizophrenic patients. Clin Neuropharmacol. 2005 Nov-Dec;28(6):265-9.

24. Rabkin JG, McElhiney MC, Rabkin R, McGrath PJ, Ferrando SJ. Placebo-controlled trial of dehydroepiandrosterone (DHEA) for treatment of nonmajor depression in patients with HIV/AIDS. Am J Psychiatry. 2006 Jan;163(1):59-66.

25. Maninger N, Wolkowitz OM, Reus VI, Epel ES, Mellon SH. Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS). Front Neuroendocrinol. 2009 Jan;30(1):65-91.

26. Mo Q, Lu S, Garippa C, Brownstein MJ, Simon NG. Genome-wide analysis of DHEA- and DHT-induced gene expression in mouse hypothalamus and hippocampus. J Steroid Biochem Mol Biol. 2009 Apr;114(3-5):135-43.

27. Pinnock SB, Lazic SE, Wong HT, Wong IH, Herbert J. Synergistic effects of dehydroepiandrosterone and fluoxetine on proliferation of progenitor cells in the dentate gyrus of the adult male rat. Neuroscience. 2009 Feb 18;158(4):1644-51.

28. Baulieu EE, Thomas G, Legrain S, et al. Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4279-84.

29. Jankowski CM, Gozansky WS, Kittelson JM, Van Pelt RE, Schwartz RS, Kohrt WM. Increases in bone mineral density in response to oral dehydroepiandrosterone replacement in older adults appear to be mediated by serum estrogens. J Clin Endocrinol Metab. 2008 Dec;93(12):4767-73.

30. von Muhlen D, Laughlin GA, Kritz-Silverstein D, Bergstrom J, Bettencourt R. Effect of dehydroepiandrosterone supplementation on bone mineral density, bone markers, and body composition in older adults: the DAWN trial. Osteoporos Int. 2008 May;19(5):699-707.

31. Weiss EP, Shah K, Fontana L, Lambert CP, Holloszy JO, Villareal DT. Dehydroepiandrosterone replacement therapy in older adults: 1- and 2-y effects on bone. Am J Clin Nutr. 2009 May;89(5):1459-67.

32. Buford TW, Willoughby DS. Impact of DHEA(S) and cortisol on immune function in aging: a brief review. Appl Physiol Nutr Metab. 2008 Jun;33(3):429-33.

33. Kim SK, Shin MS, Jung BK, et al. Effect of dehydroepiandrosterone on lipopolysaccharide-induced interleukin-6 production in DH82 cultured canine macrophage cells. J Reprod Immunol. 2006 Jun;70(1-2):71-81.

34. Nawata H, Yanase T, Goto K, Okabe T, Ashida K. Mechanism of action of anti-aging DHEA-S and the replacement of DHEA-S. Mech Ageing Dev. 2002 Apr 30;123(8):1101-6.

35. Frantz MC, Prix NJ, Wichmann MW, et al. Dehydroepiandrosterone restores depressed peripheral blood mononuclear cell function following major abdominal surgery via the estrogen receptors. Crit Care Med. 2005 Aug;33(8):1779-86.

36. Marcu AC, Paccione KE, Barbee RW, et al. Androstenetriol immunomodulation improves survival in a severe trauma hemorrhage shock model. J Trauma. 2007 Sep;63(3):662-9.

37. Oberbeck R, Deckert H, Bangen J, Kobbe P, Schmitz D. Dehydroepiandrosterone: a modulator of cellular immunity and heat shock protein 70 production during polymicrobial sepsis. Intensive Care Med. 2007 Dec;33(12):2207-13.

38. Burdick NC, Dominguez JA, Welsh TH, Jr., Laurenz JC. Oral administration of dehydroepiandrosterone-sulfate (DHEAS) increases in vitro lymphocyte function and improves in vivo response of pigs to immunization against keyhole limpet hemocyanin (KLH) and ovalbumin. Int Immunopharmacol. 2009 Jul 29.

39. Mills SJ, Ashworth JJ, Gilliver SC, Hardman MJ, Ashcroft GS. The sex steroid precursor DHEA accelerates cutaneous wound healing via the estrogen receptors. J Invest Dermatol. 2005 Nov;125(5):1053-62.

40. Romanutti C, Bruttomesso AC, Castilla V, Bisceglia JA, Galagovsky LR, Wachsman MB. In vitro antiviral activity of dehydroepiandrosterone and its synthetic derivatives against vesicular stomatitis virus. Vet J. 2009 Nov;182(2):327-35.

41. Acosta EG, Bruttomesso AC, Bisceglia JA, Wachsman MB, Galagovsky LR, Castilla V. Dehydroepiandrosterone, epiandrosterone and synthetic derivatives inhibit Junin virus replication in vitro. Virus Res. 2008 Aug;135(2):203-12.

42. Santos CD, Toldo MP, Santello FH, Filipin Mdel V, Brazão V, do Prado Júnior JC. Dehydroepiandrosterone increases resistance to experimental infection by Trypanosoma cruzi. Vet Parasitol. 2008 May 31;153(3-4):238-43.

43. Brazão V, Santello FH, Caetano LC, Del Vecchio Filipin M, Paula Alonso Toldo M, do Prado JC, Jr. Immunomodulatory effects of zinc and DHEA on the Th-1 immune response in rats infected with Trypanosoma cruzi. Immunobiology. 2009 Jul 4.

44. Caetano LC, Santello FH, Del Vecchio Filipin M, et al. Trypanosoma cruzi: dehydroepiandrosterone (DHEA) and immune response during the chronic phase of the experimental Chagas’ disease. Vet Parasitol. 2009 Jul 7;163(1-2):27-32.

45. Harding G, Mak YT, Evans B, Cheung J, MacDonald D, Hampson G. The effects of dexamethasone and dehydroepiandrosterone (DHEA) on cytokines and receptor expression in a human osteoblastic cell line: potential steroid-sparing role for DHEA. Cytokine. 2006 Oct;36(1-2):57-68.

46. Choi IS, Cui Y, Koh YA, Lee HC, Cho YB, Won YH. Effects of dehydroepiandrosterone on Th2 cytokine production in peripheral blood mononuclear cells from asthmatics. Korean J Intern Med. 2008 Dec;23(4):176-81.

47. Hansen PA, Han DH, Nolte LA, Chen M, Holloszy JO. DHEA protects against visceral obesity and muscle insulin resistance in rats fed a high-fat diet. Am J Physiol. 1997 Nov;273(5 Pt 2):R1704-1708.

48. Richards RJ, Porter JR, Svec F. Long-term oral administration of dehydroepiandrosterone has different effects on energy intake of young lean and obese male Zucker rats when compared to controls of similar metabolic body size. Diabetes Obes Metab. 1999 Jul;1(4):233-9.

49. Ponholzer A, Madersbacher S, Rauchenwald M, Jungwirth S, Fischer P, Tragl KH. Vascular risk factors and their association to serum androgen levels in a population-based cohort of 75-year-old men over 5 years: results of the VITA study. World J Urol. 2009 Jun 28.

50. Tagliaferro AR, Davis JR, Truchon S, Van Hamont N. Effects of dehydroepiandrosterone acetate on metabolism, body weight and composition of male and female rats. J Nutr. 1986 Oct;116(10):1977-83.

51. Poczatková H, Bogdanová K, Uherková L, et al. Dehydroepiandrosterone effects on the mRNA levels of peroxisome proliferator-activated receptors and their coactivators in human hepatoma HepG2 cells. Gen Physiol Biophys. 2007 Dec;26(4):268-74.

52. Karbowska J, Kochan Z. Effect of DHEA on endocrine functions of adipose tissue, the involvement of PPAR gamma. Biochem Pharmacol. 2005 Jul 15;70(2):249-57.

53. Smith KJ, Skelton HG. Peroxisomal proliferator-activated ligand therapy for HIV lipodystrophy. Clin Exp Dermatol. 2001 Mar;26(2):155-61.

54. Kochan Z, Karbowska J. Dehydroepiandrosterone up-regulates resistin gene expression in white adipose tissue. Mol Cell Endocrinol. 2004 Apr 15;218(1-2):57-64.

55. de Heredia FP, Cerezo D, Zamora S, Garaulet M. Effect of dehydroepiandrosterone on protein and fat digestibility, body protein and muscular composition in high-fat-diet-fed old rats. Br J Nutr. 2007 Mar;97(3):464-70.

56. de Heredia FP, Larque E, Zamora S, Garaulet M. Dehydroepiandrosterone modifies rat fatty acid composition of serum and different adipose tissue depots and lowers serum insulin levels. J Endocrinol. 2009 Apr;201(1):67-74.

57. Yorek MA, Coppey LJ, Gellett JS, et al. Effect of treatment of diabetic rats with dehydroepiandrosterone on vascular and neural function. Am J Physiol Endocrinol Metab. 2002 Nov;283(5):E1067-1075.

58. Sato K, Iemitsu M, Aizawa K, Ajisaka R. DHEA improves impaired activation of Akt and PKC zeta/lambda-GLUT4 pathway in skeletal muscle and improves hyperglycaemia in streptozotocin-induced diabetes rats. Acta Physiol (Oxf). 2009 Nov;197(3):217-25.

59. Brignardello E, Runzo C, Aragno M, et al. Dehydroepiandrosterone administration counteracts oxidative imbalance and advanced glycation end product formation in type 2 diabetic patients. Diabetes Care. 2007 Nov;30(11):2922-7.

60. Ponikowska B, Jankowska EA, Maj J, et al. Gonadal and adrenal androgen deficiencies as independent predictors of increased cardiovascular mortality in men with type II diabetes mellitus and stable coronary artery disease. Int J Cardiol. 2009 Apr 21.

61. Cappola AR, O’Meara ES, Guo W, Bartz TM, Fried LP, Newman AB. Trajectories of dehydroepiandrosterone sulfate predict mortality in older adults: the cardiovascular health study. J Gerontol A Biol Sci Med Sci. 2009 Dec;64(12):1268-74.

62. Srinivasan M, Irving BA, Dhatariya K, et al. Effect of dehydroepiandrosterone replacement on lipoprotein profile in hypoadrenal women. J Clin Endocrinol Metab. 2009 Mar;94(3):761-4.

63. Ii M, Hoshiga M, Negoro N, et al. Adrenal androgen dehydroepiandrosterone sulfate inhibits vascular remodeling following arterial injury. Atherosclerosis. 2009 Sep;206(1):77-85.

64. Aragno M, Meineri G, Vercellinatto I, et al. Cardiac impairment in rabbits fed a high-fat diet is counteracted by dehydroepiandrosterone supplementation. Life Sci. 2009 Jul 3;85(1-2):77-84.

65. Mitchell GF. Effects of central arterial aging on the structure and function of the peripheral vasculature: implications for end-organ damage. J Appl Physiol. 2008 Nov;105(5):1652-60.

66. Stomati M, Monteleone P, Casarosa E, et al. Six-month oral dehydroepiandrosterone supplementation in early and late postmenopause. Gynecol Endocrinol. 2000 Oct;14(5):342-63.

67. Brooke AM, Kalingag LA, Miraki-Moud F, et al. Dehydroepiandrosterone improves psychological well-being in male and female hypopituitary patients on maintenance growth hormone replacement. J Clin Endocrinol Metab. 2006 Oct;91(10):3773-9.

68. Nordmark G, Bengtsson C, Larsson A, Karlsson FA, Sturfelt G, Rönnblom L. Effects of dehydroepiandrosterone supplement on health-related quality of life in glucocorticoid treated female patients with systemic lupus erythematosus. Autoimmunity. 2005 Nov;38(7):531-40.

69. Hackbert L, Heiman JR. Acute dehydroepiandrosterone (DHEA) effects on sexual arousal in postmenopausal women. J Womens Health Gend Based Med. 2002 Mar;11(2):155-62.

70. Lee SY, Myung SC, Lee MY, et al. The effects of dehydroepiandrosterone (DHEA)/DHEA-sulfate (DHEAS) on the contraction responses of the clitoral cavernous smooth muscle from female rabbits. J Sex Med. 2009 Oct;6(10):2653-60.

71. Lee KS, Oh KY, Kim BC. Effects of dehydroepiandrosterone on collagen and collagenase gene expression by skin fibroblasts in culture. J Dermatol Sci. 2000 Jun;23(2):103-10.

72. Calvo E, Luu-The V, Morissette J, et al. Pangenomic changes induced by DHEA in the skin of postmenopausal women. J Steroid Biochem Mol Biol. 2008 Dec;112(4-5):186-93.

Boston Testosterone is uniquely positioned to quickly conduct Hormone testing for men nationwide. If you are interested in having a National Hormone Physician order testing for you, please contact Boston Testosterone online.

Boston Testosterone is a Testosterone Replacement, Wellness and Preventative Medicine Medical Center that treats and prevents the signs and symptoms associated with Andropause and hormone imbalances. With affiliates nationally, Boston Testosterone offers hormone replacement therapy, weight loss protocols, erectile dysfunction (ED), Sermorelin-GHRP2 therapy and neutraceutical injectable therapies for men and women. Their medical facilities offer physician examinations and treatment programs that incorporate the latest in medical science.

“The Greatest Health of Your Life” ℠

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www.BostonTestosterone.com

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Boston Testosterone Partners – A new study finds that a drop in testosterone levels over time is more likely to result from a man’s behavioral and health changes than by aging.

“Declining testosterone levels are not an inevitable part of the aging process, as many people think,” said study co-author Gary Wittert, MD, professor of medicine at the University of Adelaide in Adelaide, Australia. “Testosterone changes are largely explained by smoking behavior and changes in health status, particularly obesity and depression.”

Many older men have low levels of the sex hormone testosterone , but the cause is not known. Few population-based studies have tracked changes in testosterone levels among the same men over time, as their study did, Wittert said.

In this study, supported by the National Health and Medical Research Council of Australia, the authors analyzed testosterone measurements in more than 1,500 men who had measurements taken at two clinic visits five years apart. All blood testosterone samples underwent testing at the same time for each time point, according to Wittert.

After the researchers excluded from the analysis any men who had abnormal lab values or who were taking medications or had medical conditions known to affect hormones, they included 1,382 men in the data analysis. Men ranged in age from 35 to 80 years, with an average age of 54.

On average, testosterone levels did not decline significantly over five years; rather, they decreased less than 1 percent each year, the authors reported. However, when the investigators analyzed the data by subgroups, they found that certain factors were linked to lower testosterone levels at five years than at the beginning of the study.

“Men who had declines in testosterone were more likely to be those who became obese, had stopped smoking or were depressed at either clinic visit,” Wittert said. “While stopping smoking may be a cause of a slight decrease in testosterone, the benefit of quitting smoking is huge.”

Past research has linked depression and low testosterone . This hormone is important for many bodily functions, including maintaining a healthy body composition, fertility and sex drive. “It is critical that doctors understand that declining testosterone levels are not a natural part of aging and that they are most likely due to health-related behaviors or health status itself,” he said.

Unmarried men in the study had greater testosterone reductions than did married men. Wittert attributed this finding to past research showing that married men tend to be healthier and happier than unmarried men. “Also, regular sexual activity tends to increase testosterone ,” he explained.

Source: The Endocrine Society

Boston Testosterone is a Testosterone Replacement , Wellness and Preventative Medicine Medical Center that treats and prevents the signs and symptoms associated with Andropause and hormone imbalances. With affiliates nationally, Boston Testosterone offers hormone replacement therapy, weight loss protocols, erectile dysfunction (ED), Sermorelin-GHRP2 therapy and neutraceutical injectable therapies for men and women. Their medical facilities offer physician examinations and treatment programs that incorporate the latest in medical science.

“The Greatest Health of Your Life” ℠

Boston Testosterone Partners/ Core New England

www.BostonTestosterone.com

www.facebook.com/BostonTestosterone

781-269-5953

cblaisdell@corenewengland.com

SERMORELIN GHRP2

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Boston Testosterone Partners /Core New England

Our state-of-the-art compounding pharmacy has focused their considerable knowledge on producing a Second Generation HGH medication that delivers greater benefits to the patient at a price that is far more affordable than rHGH. Our exciting new product, SERMORELIN GHRP2 , has proven to be much more effective and have a more profound effect on body composition.

When combined with our Testosterone Replacement Therapy protocols, the results are amazing…

When we’re young, our bodies produce a growth hormone releasing factor that triggers our pituitary gland to produce and release human growth hormone (hGH) in levels that are sufficient to sustain good health and vitality. However, as we age, growth hormone releasing factor declines causing a decrease in the production and secretion of pituitary hGH. This often results in a growth hormone deficiency that can erode health, diminish vigor and vitality, and lead to a host of undesirable symptoms.

A Natural, Effective, Affordable Alternative

Traditionally, adult growth hormone deficiency (AGHD) has been treated by substituting natural hGH with recombinant human growth hormone (rhGH). Now, our breakthrough product, SERMORELIN GHRP2 offers a natural, effective, and affordable alternative to recombinant human growth hormone for those suffering the symptoms of age-related growth hormone deficiency.

Developed in 1998 by Serono Laboratories, Inc., the makers of Saizen hGH, FDA approved Sermorelin is the most natural and effective treatment for AGHD. As a releasing agent, SERMORELIN GHRP2 triggers the pituitary gland to produce your own natural growth hormone. Your body regulates the level and frequency of hGH release, so you don’t experience the side effects associated with injected rhGH.

No need to cycle on/off Sermorelin GHRP2

SERMORELIN GHRP2 requires no off-cycles. In fact, the longer you use it, the better your pituitary gland functions, more like it did when you were younger!! In addition, SERMORELIN GHRP2 can be used to re-stimulate the natural production of human growth hormone, making it a very effective off-cycle medication for those on an injected rhGH therapy program.

At our pharmacy, we’ve combined the pituitary-supporting effects of Sermorelin with the stimulating action of GHRP-2 (Growth Hormone Releasing Peptide). GHRP-2 stimulates the pituitary gland which causes an increase in growth hormone release. In addition to amplifying your GH releasing Hormone, GHRP-2 also acts to suppress other hormones that inhibit your body’s natural growth hormone secretion. GHRP-2 also supports your central nervous system by protecting neurons, as well as, increasing strength similar to the way certain steroids in the dihydrotestosterone family do.

As detailed below, our SERMORELIN GHRP2 will include the following benefits:

• Increases Energy, Provides Mental Clarity and Improves Mood
• Improves Physical and Mental Functioning
• Improves Immune System, Skin Elasticity and Strengthens Hair
• Huge Metabolism Increases
• Improves Cholesterol levels, Lowers Blood Pressure, Protects the Heart
• Decreases Body Fat
• Increases lean muscle mass

Restore Your Health and Vitality!

Bottom line, restoring optimal growth hormone levels can sustain and promote youthful anatomy and physiology, thereby helping to restore the health and vitality often lost with age-related growth hormone deficiency. SERMORELIN GHRP2 not only provides the youth restoring benefits of hGH on body composition, it also helps maintain good pituitary health.

Now available with GHRP-6 included for a greater natural HGH release.

For More Information the Boston Testosterone Partners Website or email us at CBlaisdell@corenewengland.com

To read all our success stories, visit our Facebook Wall.

What to Expect from Sermorelin GHRP2 therapy…

If you follow the guidelines set out by our Doctor and exercise regularly with a clean diet, you can expect to see these dramatic changes from your increased HGH levels as soon as 3-6 months from beginning your therapy……

1. Benefits to the Immune System

A major benefit of increasing HGH levels is that an increase of the hormone can actually give the immune system a powerful boost; resetting it to back when it was strongest in our younger years. You may be wondering how this is possible. It’s simple, really. I’ll try to explain: The Human Growth Hormone regenerates cells. White blood cells, which help fight disease, are increased and the production of red blood cells is enhanced. Also, macrophages needed to defend against bacteria are boosted. New antibodies are created and the production of interleukin 2 and T-cells is elevated.

Explanation of Benefit:

Basically this means you’ll encounter significantly fewer infections, colds, flues or other maladies that will try to slow you down. If you do get sick, which everyone does once in a while, the time it takes for you to recover is shortened. Surprisingly, these positive effects on the immune system are often the most frequently overlooked set of benefits associated with successful HGH therapy.

2. HGH Benefits Lean Muscle Growth

Who doesn’t want more lean muscle and less fat? HGH benefits more than the immune system after all. It helps people enhance their physical presence by gaining weight in all the right places. Not to worry, weight gained is in muscle not fat.

Our research in action:

According to recent research, people who take this hormone decrease their body fat by an impressive average of 15%. What’s even better, the research also concluded that people increased their amount of lean muscle by an average of 8% by supplementing their daily regiments with a human growth hormone supplement.

Power Users: If your primary objective is to speed up muscle growth, stimulate new muscle development by increasing protein synthesis, or to increase your overall muscle strength, you should read our popular article on using HGH for Bodybuilding and other performance enhancing purposes.

It doesn’t hurt that your metabolism will get a boost allowing you to burn calories at a faster rate. The calories that would have once contributed to your love handles, thighs, and abs are now converted into fuel used to build lean muscle. Losing unwanted fat not only makes you look and feel better, it can make you look years younger as well.

3. HGH Benefits Your Endurance Levels

Let’s face it, we live in a fast paced society that never slows down no matter how tired we get. HGH benefits our overall endurance levels by providing needed energy and vitality. Your moods get better and your outlook on life gets brighter, all stemming from the use of natural HGH supplements in increase your body’s natural hormone level.

Interesting Fact: This mood-elevating benefit is a natural byproduct of healthy body systems, found after a successful increase of existing growth hormone levels. Some users have compared this natural effect to the effects of prescription anti-depressants that synthetically create feelings of well-being and happiness in clinically depressed men and women).

Your expectations and attitudes will become invigorated as your concentration and ability to think things through skyrockets. With the right attitude and ability to keep your thoughts in check, not only will you be able to make it through an endurance packed workout, you won’t struggle to pay attention at work, in class or anywhere else in your life.

These particular benefits are our personal favorites. It’s not often that you hear about something that can naturally elevate your mood and outlook on life as well as HGH can.

We’ve analyzed countless sources of data and information on various efficiency studies and clinical trials and the results almost never change. The facts are consistent between research: Skin, nails and hair all reap the benefits of elevated growth hormone levels–caused by successful HGH optimization as an adult.

Think about this: What would you say if you could make your face look a decade younger?

4. Effects on Skin

You look younger because wrinkles are reduced. The skin on your face thickens. Contours are more noticeable and youthful looking, hydration and elasticity sets in. In some documented cases, burned skin is repaired and ulcerated wounds close. Fine lines fade and deep, set in wrinkles become less noticeable all due to cell rejuvenation.

5. Effects on Finger and Toenails

Nails grow stronger and longer. This is possible because cellulite patches disappear. Nail beds are healthier and cuticles stronger.

6. Effects on Hair Growth

Thanks to the countless benefits of HGH, your hair begins to grow in its natural shade of color and it also grows in thicker and stronger. One study attributed new hair growth in 38% of its clinical participants to HGH supplementation. Pretty impressive, right?

7. Improvements in Sex Drive

As the body ages, its natural to experience a decrease in sex drive. HGH benefits sex drive in both men and women. Both sexes have reported a significant increase in enhanced orgasms. The want/desire to have sex returns and both men and women are able to perform when the desire and opportunity presents itself.

8. Sexual-Health Benefits of HGH:

Sexual Function Returns

Vaginal Dryness Disappears

Multiple Orgasms

Menstrual and Post-Menstrual Symptoms Decrease

Heightened Pleasure

Increased Male Potency

In humans who have an unnatural deficiency of their growth hormone levels, frequent problems arise relating to lack of sexual libido or sexual desires of any kind. GH-deficient males have trouble producing and maintaining erections and GH-deficient females have extra trouble getting in the mood for sexual activity. Having an orgasm is often impossible for individuals with severe deficiencies.

9. HGH Benefits Brain Function

This whole section is an astonishing concept that I still have trouble believe sometimes. The fact that we can naturally increase the power of the human mind (without the negative side effects of harmful stimulants) is almost too hard to believe, even for a researcher like myself. Sometimes I have to just take a step back from everything and think about how far we’ve come with medical advancements in the past century.

How does HGH increase brain power?

Without neurons, our brain and nervous systems wouldn’t be able to function properly. As we age, neurons can become damaged and slow down. Neurons are a permanent fixture and though we cannot grow new neurons, thanks to HGH, we can rejuvenate and repair the ones we have.

Explanation of Benefit:

The health of your neurons drastically affects your ability to learn, call memories to action and be as intelligent as you set out to be. Living with unhealthy neurons in the brain can cause many stressful situations where cognitive performance is less than satisfactory. By supplementing your body with additional growth hormone, you can gradually restore the health of such neurons in your brain.

Just another benefit to add to the long list: Human Growth Hormone has the ability to enhance cellular defense mechanisms. This defense mechanism prevents free radicals from doing their damage to cells and promotes a typical increase in healthiness of the human body.

Did you know HGH can also stimulate brain cells into rejuvenating themselves?

That’s pretty cool, right? All of these benefits are possible since the human growth hormone is naturally produced in the body at an early age. By increasing the levels of HGH as an adult, we can virtually reset the clock on our lives and give our body systems the youthful reminder they need to keep producing natural goodies. Anyway, let’s go back to the topic of HGH stimulating brain cells and promoting rejuvenation.

What does this enhance?

Short-Term Abilities

Long-Term Abilities

Memories

Learning

Intelligence

THE BEST INVESTMENT WE CAN MAKE IS THE ONE WE MAKE IN OUR HEALTH.

CALL BOSTON TESTOSTERONE PARTNERS/CORE NEW ENGLAND 855-617-MEDS (6337)/781-269-5953

TO START ON YOUR WAY TODAY!!!

Boston Testosterone Partners

Boston, Massachusetts – In addition to ED (Erectile Dysfunction) being troublesome for millions of men nationwide, it is very often a sign of low testosterone levels , as well as serious disease in men. ED has been linked to coronary artery disease and diabetes.

Shockingly, ED increases the risk of heart attack and stroke by 45 percent in men. Much the same as smoking and a family history of heart disease, ED is also predictive value for a heart attack.

While drugs like Viagra and Cialis can mask the issue as a temporary fix, what many Primary Care Doctors have missed is the diagnosis of the root, or underlying, cause. Low testosterone, poor blood vessels, metabolic health and lifestyle are critical issues to be addressed by doctors.

If you are a man of 30 years of age and feel you may be suffering from ED, Low Testosterone, Hypogonadism or Andropause, contact Boston Testosterone Partners today for a consult on how you can get tested and treated for Testosterone Replacement Therapy .

Boston Testosterone is a Testosterone Replacement, Wellness and Preventative Medicine Medical Center that treats and prevents the signs and symptoms associated with Andropause and hormone imbalances. With affiliates nationally, Boston Testosterone offers hormone replacement therapy, weight loss protocols, erectile dysfunction (ED), Sermorelin-GHRP2 therapy and neutraceutical injectable therapies for men and women. Their medical facilities offer physician examinations and treatment programs that incorporate the latest in Testosterone Therapy and medical sciences.

Boston Testosterone

“The Greatest Health of Your Life” ℠

Boston Testosterone Partners

www.BostonTestosterone.com

www.facebook.com/BostonTestosterone

855.617.MEDS (6337)/781-269-5953