DHEA or Dehydroepiandrosterone, is the most abundant steroid found in the human blood stream. It is also one of the most reliable bio-markers of aging. DHEA is secreted by the adrenal glands, and also produced in the gonads (testes and ovaries), and the brain. It is sometimes called the “mother of all hormones” because it is the building block from which estrogen, progesterone and testosterone are produced, and is vital to health. Thousands of scientific article have been published on DHEA during the last 50 years, but a clear picture of its role in human health didn’t begin to merge until the 1990’s.
DHEA exhibits an amazingly wide diversity of effects!
DHEA has been reported to have anti-diabetic, anti-dementia, anti-obesity, anti-carcinogenic, anti-stress, immune-enhancing, anti-viral and anti-bacterial, anti-aging and anti-heart disease effects. In addition, research has shown that DHEA:
- Is an anti-oxidant
- Decreases body fat
- Is a hormone regulator (it helps regulate the thyroid & pituitary glands, and enhances thymus gland function)
- Decreases cholesterol
- Stimulates the production of Human growth hormone
- Boost immunity by stimulating killer cell activity (alleviation of symptoms inpatients with Lupus, Chronic fatigue syndrome, Rheumatoid arthritis etc)
- Increases the sensitivity of cells to insulin
- Assists in returning the body to a balanced state after a stress reaction
- Improves cognitive function, bone formation and libido
- Enhances mood by increasing the brain’s serotonin level
DHEA Levels Decrease With Age
Your DHEA levels vary throughout your life, and naturally decline as you get older.
We produce large amounts when we are young, and research shows that children’s brains require a significant amount of DHEA to grow and develop. DHEA levels peak at age 25 and decline at a rate of about 2% a year, thereafter. It isn’t until the mid forties, however, that we begin to the effects of lower DHEA levels. By age 80, most people’s DHEA blood levels are only about 15% of where they were during their 20’s. By the time we’re 90, DHEA levels are down to 5%
DHEA Deficiency
Symptoms of DHEA deficiency include: poor memory, poor resistance to noise,
anxiety, Lack of motivation, decreased libido, decreased armpit and pubic hair, and
dry skin, eyes or hair.
Very low levels of DHEA have been linked to Cardio-vascular disease in men, some
cancers, trauma, and stress; Research has shown has shown that Alzheimer patients
have exhibited low DHEA levels, when compared to their healthy counterparts.
Other Factors that contribute to decreased DHEA levels:
- Chronic disease
- Excessive sugar intake
- Nicotine
- Caffeine
- Alcohol
- Nutritional imbalances
- A vegetarian diet low in cholesterol and healthy fats
Recommended Doses of DHEA
For men: Typical safe dose of Plain DHEA range from 25-100mg daily. DHEA is a
available in a Sublingual tablet, capsule, Topical cream or injectable forms. Dosages
depend on age, symptoms and blood levels.
For Women: In order to avoid potential side effects which include Acne, Facial hair
growth, deeper voice, thinning hair and genital virilization, a maximum of 25mg
daily is recommended in divided dosage. Effective dose range from 5mg-25mg.
What Is 7-Keto DHEA?
Keto DHEA, also known as 7-Keto, is a metabolite of the adrenal hormone DHEA. But
because It doesn’t break down into the sex hormones Estrogen or Testosterone, is it
considered non-hormonal. Many of the potential side effects associated with DHEA
are avoided: such as Acne, facial hair growth in women and hair loss.
Functions of 7-Keto DHEA include:
- Increases muscle mass
- Decreases stress
- Increases metabolic rate by increase levels of Free T3
- Accelerate weight loss in healthy adult
Weight Loss
7-Keto DHEA has clinically been shown to increase metabolism and contribute to healthy weight loss. One way that 7-Keto contributes to weight loss is by increasing the activity of thermogenic enzymes responsible for fatty acid oxidation. 7-Keto has been shown to accelerate fat loss threefold without any stimulant effect on the body.
It takes between 200mg-400mg in divided dosages a day, accompanied by balanced diet (calorie restriction) and exercise in order to loose significant fat and enhance muscle mass. For women, 100mg twice/day of 7-Keto DHEA is usually enough. Very low levels of DHEA have been linked to Cardio-vascular disease in men, some cancers, trauma, and stress; Research has shown has shown that Alzheimer patients have exhibited low DHEA levels, when compared to their healthy counterparts.
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